DMG - Improve of immune function, speech, awareness and attention?

Amino acid DMG (synonyms: N,N-dimethylglycine, N,N-dimethylamino acetic acid, N-methylsarcosine) is a dimethylated form of the amino acid, glycine, and is metabolically related to choline.

Small amounts of this substance can be found in the body. During cell production, the derivative acts as an intermediary in the choline-to-glycine metabolism process. The small intestine absorbs dimethylglycine before it transfers to the liver. Dimethylglycine also appears naturally as a derivative in animal and plant cells.

DMG reportedly may:

• boost energy and improve athletic performance
• vastly improve immune system function, whilst inhibiting immune system response
• reduce stress
• help control seizures
• improve cardiovascular health
• lower blood cholesterol, blood sugar, and blood pressure
• improve neurological function and mental clarity (aging and senility)
• treat symptoms of attention deficit hyperactivity disorder (ADHD)
• support balanced behavior
• help those with autism improve in their speech and behavior patterns - there are claims that it can improve eye contact, frustration tolerance, speech and interest in interacting socially, as well as decreasing aggressive behaviour toward self and others in severe cases.
• treat symptoms of chronic fatigue syndrome
• improve sexual function
• help by treating problems with alcoholism and drug addiction

Sources of DMG

In addition to plant and animal cells, DMG may be found naturally in vitamin B-rich foods. It is closely linked to B15 and it increases Pangamic Acid production in the body. Some of the most common food sources include liver, beef blood, apricot kernels, brewer´s yeast, beans, cereals, grains, brown rice, pumpkin seeds, and sunflower seeds also contain specified amounts of the amino acid derivative.

Today, you can buy DMG supplements and medicines from many pharmacies and drugstores.

N,N-dimethylglycine is combined hydrochloride to form the stable N,N-dimethylglycine HCl salt.

 

Side effects

DMG reportedly may cause drowsiness in some people, although medical evidence has not as yet presented any serious side effects. Dimethylglycine might be safe to use short-term, up to 28 days. The safety of long-term use is unknown.

In the 1980s, a federal court in Chicago banned the interstate sale of a brand of dimethylglycine, stating that it was an unsafe food additive. In 1994, Congress passed the Dietary Supplement Health and Education Act, or DSHEA. This caused vitamin B15 and most other dietary supplements to fall into a sort of "grey area" of regulation. Since dimethylglycine is neither a food nor a drug, it cannot be mandated by the FDA.

Research

Dimethylglycine (DMG) is hypothesized to improve speech and reduce autistic behaviors and is a commonly used supplement. Two double-blind, placebo-controlled studies found no statistically significant effect on autistic behaviors and reported few side effects. [1,2]

Another research report an effectiveness of nutritional supplements for reducing symptoms in autism-spectrum disorder, although the reported findings cannot be generalized. [3]

[1] Bolman WM, Richmond JA. A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder. J Autism Dev Disord. 1999 Jun;29(3):191-4.

[2] Angley M, Semple S, Hewton C, Paterson F, McKinnon R. Children and autism—part 2—management with complementary medicines and dietary interventions . Aust Fam Physician. 2007;36(10):827–30. PMID 17925903.

[3] Xia RR1. Effectiveness of nutritional supplements for reducing symptoms in autism-spectrum disorder: a case report. J Altern Complement Med. 2011 Mar;17(3):271-4. doi: 10.1089/acm.2010.0146. Department of Physical Therapy, Creighton University, Omaha, NE 68178, USA. RuiPingXia@creighton.edu

 

Warning: Health information and the names of the drugs mentioned in the article are only for orientation in the field of self-medication and does not replace communication with your doctor. Before taking any medication, read the leaflet or ask your pharmacist or doctor. The author is not responsible for misinterpretation of the information contained on the website and is not responsible for any damages incurred subsequent procedures or conduct that are made based on the content of these pages. By entering this blog you confirm that you have read the aim and the restrictions of the site.